9f3c0f2231367957a8a46854ddd444909b6b7fbd gperez2 Thu Apr 25 17:06:46 2024 -0700 Another fix to the paragraph indentation, refs #33251 diff --git src/hg/htdocs/goldenPath/newsarch.html src/hg/htdocs/goldenPath/newsarch.html index c06c05d..6683e11 100755 --- src/hg/htdocs/goldenPath/newsarch.html +++ src/hg/htdocs/goldenPath/newsarch.html @@ -52,32 +52,32 @@

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Smaller software changes are not announced here. A summary of the three-weekly release changes can be here. For the full list of our daily code changes head to our GitHub page.

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Apr. 25, 2024    New AbSplice Prediction Scores track for hg19

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We are excited to announce the release of the AbSplice scores track that was previously only on GRCh38/hg38 and is now also available on the human GRCh37/hg19 genome assembly. AbSplice is a method that predicts aberrant splicing across human tissues, as described in Wagner, Çelik et al., 2023. This track consists of an aberrant splicing benchmark dataset that spans over 8.8 million rare variants in 49 human tissues from the Genotype-Tissue Expression (GTEx) dataset and displays precomputed AbSplice scores for all possible single-nucleotide variants genome-wide. The AbSplice score is a probability estimate of how likely aberrant splicing of some sort takes place in a given tissue. Aberrant splicing predictions for tissues that are related to disease may prove to be helpful in identifying the effector gene. The authors suggest three cutoffs which are represented by color in the track.